Sitting or lying down for more than 30 minutes at a time each day was associated with a higher risk of dying from cancer, according to a study published in PLOS Medicine. The research analysed data from more than 91,000 UK Biobank participants who wore wearable devices and were followed for an average of 12 years.
The study found that each additional hour of continuous inactivity increased the risk of cancer death by about 10 percent. Replacing one hour of sedentary time per day with light physical activity such as ironing or washing up was linked to a 12 percent lower risk of cancer death. Substituting 30 minutes of sitting with 30 minutes of moderate‑pace walking corresponded to an 8 percent reduction, and replacing five minutes of sitting with five minutes of vigorous activity was associated with a 22 percent lower risk.
The authors noted that the analysis was observational and could not prove causation. Professor Kevin McConway of the Open University, who was not involved in the research, said the findings were interesting but further investigation was needed.
The investigators said that future clinical trials could help develop personalised strategies for breaking up prolonged sitting periods.

